PrimePCR™ Probe Assay: PSMC3IP, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PSMC3IP, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PSMC3IP, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039252
Assay Design:   exonic
Chromosome Location:   17:40725496-40725615question
Amplicon Length:   90
Splice Variants Targeted:   ENST00000393795 ENST00000253789 ENST00000587209 ENST00000590760

Gene Information

This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen androgen glucocorticoid progesterone and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq Dec 2011]

Gene Symbol:   PSMC3IP
Gene Name:   PSMC3 interacting protein
Aliases:   GT198, HOP2, HUMGT198A, TBPIP
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000131470
Entrez:   29893
Chromosome Mapping:   17q21.2

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