PrimePCR™ Probe Assay: EFNA1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039491
Assay Design:   exonic
Chromosome Location:   1:155106753-155106847question
Amplicon Length:   65
Splice Variants Targeted:   ENST00000368407 ENST00000368406

Gene Information

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships ephrins are divided into the ephrin-A (EFNA) class which are anchored to the membrane by a glycosylphosphatidylinositol linkage and the ephrin-B (EFNB) class which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2 EPHA4 EPHA5 EPHA6 and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq Jul 2008]

Gene Symbol:   EFNA1
Gene Name:   ephrin-A1
Aliases:   B61, ECKLG, EFL1, EPLG1, LERK1, TNFAIP4
RefSeq:   NC_000001.10 NT_004487.19
Ensembl:   ENSG00000169242
Entrez:   1942
Chromosome Mapping:   1q21-q22

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