PrimePCR™ Probe Assay: ADAM15, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: ADAM15, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: ADAM15, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040360
Assay Design:   exonic
Chromosome Location:   1:155030531-155030727question
Amplicon Length:   76
Splice Variants Targeted:   ENST00000356955 ENST00000449910 ENST00000359280 ENST00000360674 ENST00000368412 ENST00000355956 ENST00000271836 ENST00000368413 ENST00000531455 ENST00000368410

Gene Information

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain a disintegrin-like domain as well as a EGF-like domain. Through its disintegrin-like domain this protein specifically interacts with the integrin beta chain beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq Jul 2008]

Gene Symbol:   ADAM15
Gene Name:   ADAM metallopeptidase domain 15
Aliases:   MDC15
RefSeq:   NC_000001.10 NG_027536.1 NT_004487.19
Ensembl:   ENSG00000143537
Entrez:   8751
Chromosome Mapping:   1q21.3

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