PrimePCR™ Probe Assay: AGMO, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: AGMO, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: AGMO, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040381
Assay Design:   exonic
Chromosome Location:   7:15405139-15405768question
Amplicon Length:   79
Splice Variants Targeted:   ENST00000342526 ENST00000407277 ENST00000418075

Gene Information

Alkylglycerol monooxygenase (AGMO; EC 1.14.16.5) cleaves the O-alkyl bonds of ether lipids which are essential components of brain membranes and function in cell signaling and other critical biologic processes. The reaction catalyzed by AGMO is dependent on tetrahydrobiopterin a metabolite structurally related to the vitamins folic acid and riboflavin (summary by Watschinger et al. 2010 [PubMed 20643956]).[supplied by OMIM Feb 2011]

Gene Symbol:   AGMO
Gene Name:   alkylglycerol monooxygenase
Aliases:   FLJ16237, MGC131748, TMEM195
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000187546
Entrez:   392636
Chromosome Mapping:   7p21.2

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