PrimePCR™ Probe Assay: RPS4X, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040570
Assay Design:   exonic
Chromosome Location:   X:71492443-71492592question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000316084

Gene Information

Cytoplasmic ribosomes organelles that catalyze protein synthesis consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4 a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene namely this gene and ribosomal protein S4 Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however this hypothesis is controversial. As is typical for genes encoding ribosomal proteins there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq Jul 2008]

Gene Symbol:   RPS4X
Gene Name:   ribosomal protein S4, X-linked
Aliases:   CCG2, DXS306, FLJ40595, RPS4, S4, SCAR, SCR10
RefSeq:   NC_000023.10 NG_012524.1 NT_011669.17
Ensembl:   ENSG00000198034
Entrez:   6191
Chromosome Mapping:   Xq13.1

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