PrimePCR™ Probe Assay: FOLR3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: FOLR3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FOLR3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040705
Assay Design:   exonic
Chromosome Location:   11:71850700-71850892question
Amplicon Length:   163
Splice Variants Targeted:   ENST00000445078 ENST00000456237 ENST00000442948

Gene Information

This gene encodes a member of the folate receptor (FOLR) family members of which have a high affinity for folic acid and for several reduced folic acid derivatives and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This gene includes two polymorphic variants; the shorter one has two base deletion in the CDS resulting in a truncated polypeptide compared to the longer one. Both protein products are constitutively secreted in hematopoietic tissues and are potential serum marker for certain hematopoietic malignancies. The longer protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins respectively. [provided by RefSeq Jul 2008]

Gene Symbol:   FOLR3
Gene Name:   folate receptor 3 (gamma)
Aliases:   FR-G, FR-gamma, gamma-hFR
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000110203
Entrez:   2352
Chromosome Mapping:   11q13

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