PrimePCR™ Probe Assay: EDA, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: EDA, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: EDA, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040822
Assay Design:   exonic
Chromosome Location:   X:68836324-68836543question
Amplicon Length:   190
Splice Variants Targeted:   ENST00000525810 ENST00000527388 ENST00000374553 ENST00000374552 ENST00000524573 ENST00000338901 ENST00000377246 ENST00000349847

Gene Information

The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein which belongs to the tumor necrosis factor family acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia anhidrotic which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   EDA
Gene Name:   ectodysplasin A
Aliases:   ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, ODT1, STHAGX1, XHED, XLHED
RefSeq:   NC_000023.10 NG_021246.1 NT_011669.17 NG_009809.1
Ensembl:   ENSG00000158813
Entrez:   1896
Chromosome Mapping:   Xq12-q13.1

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