PrimePCR™ Probe Assay: DIABLO, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041684
Assay Design:   exonic
Chromosome Location:   12:122701306-122702842question
Amplicon Length:   110
Splice Variants Targeted:   ENST00000353548 ENST00000443649 ENST00000464942 ENST00000267169 ENST00000439489 ENST00000541273 ENST00000474004 ENST00000540535 ENST00000541656 ENST00000446652 ENST00000485724 ENST00000413918

Gene Information

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq Dec 2008]

Gene Symbol:   DIABLO
Gene Name:   diablo, IAP-binding mitochondrial protein
Aliases:   DIABLO-S, FLJ10537, FLJ25049, SMAC, SMAC3
RefSeq:   NC_000012.11 NT_009755.19
Ensembl:   ENSG00000184047
Entrez:   56616
Chromosome Mapping:   12q24.31

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