PrimePCR™ Probe Assay: IL17RB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049425
Assay Design:   exonic
Chromosome Location:   3:53898808-53898934question
Amplicon Length:   97
Splice Variants Targeted:   ENST00000288167 ENST00000494338

Gene Information

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation which suggested the immunoregulatory activity of this receptor. [provided by RefSeq Jul 2008]

Gene Symbol:   IL17RB
Gene Name:   interleukin 17 receptor B
Aliases:   CRL4, EVI27, IL17BR, IL17RH1, MGC5245
RefSeq:   NC_000003.11 NG_028042.1 NT_022517.18
Ensembl:   ENSG00000056736
Entrez:   55540
Chromosome Mapping:   3p21.1

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