PrimePCR™ Probe Assay: MSH4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: MSH4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: MSH4, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049429
Assay Design:   exonic
Chromosome Location:   1:76347049-76349448question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000263187

Gene Information

This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor thus provoking ADP-ATP exchange and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. [provided by RefSeq Aug 2011]

Gene Symbol:   MSH4
Gene Name:   mutS homolog 4 (E. coli)
Aliases:   Not Available
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000057468
Entrez:   4438
Chromosome Mapping:   1p31

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