PrimePCR™ Probe Assay: BCS1L, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049614
Assay Design:   exonic
Chromosome Location:   2:219525687-219525786question
Amplicon Length:   70
Splice Variants Targeted:   ENST00000428880 ENST00000430322 ENST00000456050 ENST00000359273 ENST00000392109 ENST00000392110 ENST00000423377 ENST00000392111 ENST00000412366 ENST00000439945 ENST00000431802

Gene Information

This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Five alternatively spliced transcripts encoding the same protein have been described. [provided by RefSeq Mar 2012]

Gene Symbol:   BCS1L
Gene Name:   BCS1-like (S. cerevisiae)
Aliases:   BCS, BCS1, BJS, FLNMS, GRACILE, Hs.6719, PTD, h-BCS
RefSeq:   NC_000002.11 NT_005403.17 NG_008018.1
Ensembl:   ENSG00000074582
Entrez:   617
Chromosome Mapping:   2q33

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