PrimePCR™ Probe Assay: EZR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049927
Assay Design:   exonic
Chromosome Location:   6:159206361-159206485question
Amplicon Length:   95
Splice Variants Targeted:   ENST00000337147 ENST00000367075 ENST00000392177

Gene Information

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion migration and organization and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   EZR
Gene Name:   ezrin
Aliases:   CVIL, CVL, DKFZp762H157, FLJ26216, MGC1584, VIL2
RefSeq:   NC_000006.11 NT_025741.15
Ensembl:   ENSG00000092820
Entrez:   7430
Chromosome Mapping:   6q25.3

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