PrimePCR™ Probe Assay: MADCAM1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: MADCAM1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: MADCAM1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049983
Assay Design:   exonic
Chromosome Location:   19:505043-505191question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000346144 ENST00000215637

Gene Information

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7) L-selectin and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene but the full-length nature of some variants has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   MADCAM1
Gene Name:   mucosal vascular addressin cell adhesion molecule 1
Aliases:   MACAM1
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000099866
Entrez:   8174
Chromosome Mapping:   19p13.3

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