PrimePCR™ Probe Assay: LTBR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: LTBR, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: LTBR, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050630
Assay Design:   exonic
Chromosome Location:   12:6494409-6494526question
Amplicon Length:   88
Splice Variants Targeted:   ENST00000539925 ENST00000228918 ENST00000536876 ENST00000543190 ENST00000541102

Gene Information

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types including cells of epithelial and myeloid lineages but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis. [provided by RefSeq Jul 2008]

Gene Symbol:   LTBR
Gene Name:   lymphotoxin beta receptor (TNFR superfamily, member 3)
Aliases:   CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3
RefSeq:   NC_000012.11 NT_009759.16
Ensembl:   ENSG00000111321
Entrez:   4055
Chromosome Mapping:   12p13

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