PrimePCR™ Probe Assay: ACLY, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051649
Assay Design:   exonic
Chromosome Location:   17:40070048-40075148question
Amplicon Length:   88
Splice Variants Targeted:   ENST00000319121 ENST00000352035 ENST00000590151 ENST00000537919 ENST00000393896 ENST00000592970 ENST00000353196 ENST00000297532 ENST00000482571 ENST00000272638 ENST00000569845 ENST00000564506 ENST00000567793

Gene Information

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product acetyl-CoA serves several important biosynthetic pathways including lipogenesis and cholesterogenesis. In nervous tissue ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   ACLY
Gene Name:   ATP citrate lyase
Aliases:   ACL, ATPCL, CLATP
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000131473
Entrez:   47
Chromosome Mapping:   17q21.2

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