PrimePCR™ Probe Assay: YARS, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051826
Assay Design:   exonic
Chromosome Location:   1:33241064-33241188question
Amplicon Length:   95
Splice Variants Targeted:   ENST00000373477

Gene Information

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase after it is split into two parts an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq Jul 2008]

Gene Symbol:   YARS
Gene Name:   tyrosyl-tRNA synthetase
Aliases:   CMTDIC, TYRRS, YRS, YTS
RefSeq:   NC_000001.10 NG_008408.1 NT_032977.9
Ensembl:   ENSG00000134684
Entrez:   8565
Chromosome Mapping:   1p35.1

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