PrimePCR™ Probe Assay: UBQLN1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: UBQLN1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: UBQLN1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051847
Assay Design:   exonic
Chromosome Location:   9:86292872-86293475question
Amplicon Length:   95
Splice Variants Targeted:   ENST00000376395 ENST00000257468 ENST00000529923

Gene Information

This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   UBQLN1
Gene Name:   ubiquilin 1
Aliases:   DA41, DSK2, FLJ90054, PLIC-1, UBQN, XDRP1
RefSeq:   NC_000009.11 NG_011519.1 NT_008470.19
Ensembl:   ENSG00000135018
Entrez:   29979
Chromosome Mapping:   9q22,9q21.2-q21.3

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