PrimePCR™ Probe Assay: GDF11, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: GDF11, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: GDF11, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051864
Assay Design:   exonic
Chromosome Location:   12:56142491-56142628question
Amplicon Length:   108
Splice Variants Targeted:   ENST00000257868 ENST00000546799

Gene Information

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq Jul 2008]

Gene Symbol:   GDF11
Gene Name:   growth differentiation factor 11
Aliases:   BMP-11, BMP11
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000135414
Entrez:   10220
Chromosome Mapping:   12q13.2

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