PrimePCR™ Probe Assay: SSB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: SSB, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SSB, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052098
Assay Design:   exonic
Chromosome Location:   2:170662064-170662291question
Amplicon Length:   111
Splice Variants Targeted:   ENST00000334746 ENST00000554565 ENST00000553975 ENST00000393170 ENST00000422006 ENST00000260956 ENST00000417292 ENST00000409333

Gene Information

The protein encoded by this gene is involved in diverse aspects of RNA metabolism including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion processing 5' and 3' ends of pre-tRNA precursors acting as an RNA chaperone and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. [provided by RefSeq Nov 2011]

Gene Symbol:   SSB
Gene Name:   Sjogren syndrome antigen B (autoantigen La)
Aliases:   LARP3, La
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000138385
Entrez:   6741
Chromosome Mapping:   2q31.1

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