PrimePCR™ Probe Assay: BMP2K, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: BMP2K, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: BMP2K, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052124
Assay Design:   exonic
Chromosome Location:   4:79792005-79792108question
Amplicon Length:   74
Splice Variants Targeted:   ENST00000502871 ENST00000502613 ENST00000335016

Gene Information

This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   BMP2K
Gene Name:   BMP2 inducible kinase
Aliases:   BIKE, DKFZp434K0614, DKFZp434P0116
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000138756
Entrez:   55589
Chromosome Mapping:   4q21.21

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