PrimePCR™ Probe Assay: ADCY10, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: ADCY10, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: ADCY10, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052363
Assay Design:   exonic
Chromosome Location:   1:167815258-167815366question
Amplicon Length:   79
Splice Variants Targeted:   ENST00000367851 ENST00000367848 ENST00000545172

Gene Information

The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa implying possible roles in sperm maturation through the epididymis capacitation hypermotility and/or the acrosome reaction. Genetic variations in this gene are associated with absorptive hypercalciuria type 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Nov 2009]

Gene Symbol:   ADCY10
Gene Name:   adenylate cyclase 10 (soluble)
Aliases:   HCA2, RP1-313L4.2, SAC, SACI, Sacy
RefSeq:   NC_000001.10 NT_004487.19 NG_016139.1
Ensembl:   ENSG00000143199
Entrez:   55811
Chromosome Mapping:   1q24

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