PrimePCR™ Probe Assay: CDC42BPA, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CDC42BPA, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CDC42BPA, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052421
Assay Design:   exonic
Chromosome Location:   1:227219029-227219176question
Amplicon Length:   118
Splice Variants Targeted:   ENST00000366769 ENST00000448940 ENST00000442054 ENST00000366765 ENST00000429440 ENST00000441725 ENST00000334218 ENST00000366766 ENST00000366764 ENST00000535525 ENST00000366767

Gene Information

The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described and the full-length nature of two of them has been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   CDC42BPA
Gene Name:   CDC42 binding protein kinase alpha (DMPK-like)
Aliases:   DKFZp686L1738, DKFZp686P1738, FLJ23347, KIAA0451, MRCK, MRCKA, PK428
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000143776
Entrez:   8476
Chromosome Mapping:   1q42.11

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