PrimePCR™ Probe Assay: TMEM123, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052832
Assay Design:   exonic
Chromosome Location:   11:102272818-102319543question
Amplicon Length:   91
Splice Variants Targeted:   ENST00000361236 ENST00000398136 ENST00000532161 ENST00000528969 ENST00000531103 ENST00000526676

Gene Information

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq Jul 2008]

Gene Symbol:   TMEM123
Gene Name:   transmembrane protein 123
Aliases:   KCT3, PORIMIN, PORMIN
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000152558
Entrez:   114908
Chromosome Mapping:   11q22.1

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