PrimePCR™ Probe Assay: PTDSS1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PTDSS1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PTDSS1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052989
Assay Design:   exonic
Chromosome Location:   8:97311949-97312068question
Amplicon Length:   90
Splice Variants Targeted:   ENST00000517309 ENST00000522072 ENST00000455950

Gene Information

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component PS is involved in cell signaling blood coagulation and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8) like PTDSS1 that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al. 2001 [PubMed 11084049]).[supplied by OMIM May 2009]

Gene Symbol:   PTDSS1
Gene Name:   phosphatidylserine synthase 1
Aliases:   KIAA0024, PSS1, PSSA
RefSeq:   NC_000008.10 NT_008046.16
Ensembl:   ENSG00000156471
Entrez:   9791
Chromosome Mapping:   8q22

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