PrimePCR™ Probe Assay: COX6A2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: COX6A2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: COX6A2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053009
Assay Design:   exonic
Chromosome Location:   16:31439606-31439748question
Amplicon Length:   113
Splice Variants Targeted:   ENST00000287490

Gene Information

Cytochrome c oxidase (COX) the terminal enzyme of the mitochondrial respiratory chain catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq Jul 2008]

Gene Symbol:   COX6A2
Gene Name:   cytochrome c oxidase subunit VIa polypeptide 2
Aliases:   COX6AH, COXVIAH
RefSeq:   NC_000016.9 NT_010393.16
Ensembl:   ENSG00000156885
Entrez:   1339
Chromosome Mapping:   16p

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