PrimePCR™ Probe Assay: CACNA2D3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CACNA2D3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CACNA2D3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053034
Assay Design:   exonic
Chromosome Location:   3:54537530-54537666question
Amplicon Length:   107
Splice Variants Targeted:   ENST00000474759 ENST00000490478 ENST00000492460 ENST00000415676 ENST00000288197

Gene Information

This gene encodes a member of the alpha-2/delta subunit family a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1 alpha-2/delta beta and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   CACNA2D3
Gene Name:   calcium channel, voltage-dependent, alpha 2/delta subunit 3
Aliases:   HSA272268
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000157445
Entrez:   55799
Chromosome Mapping:   3p21.1

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