PrimePCR™ Probe Assay: FYCO1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: FYCO1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FYCO1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053401
Assay Design:   exonic
Chromosome Location:   3:45963206-45963302question
Amplicon Length:   67
Splice Variants Targeted:   ENST00000433878 ENST00000296137 ENST00000438446 ENST00000535325

Gene Information

This gene encodes a protein that contains a RUN domain FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7 phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq Dec 2011]

Gene Symbol:   FYCO1
Gene Name:   FYVE and coiled-coil domain containing 1
Aliases:   DKFZp779K1152, FLJ13335, MGC126517, MGC126519, RUFY3, ZFYVE7
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000163820
Entrez:   79443
Chromosome Mapping:   3p21.31

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