PrimePCR™ Probe Assay: THBD, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: THBD, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: THBD, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054589
Assay Design:   exonic
Chromosome Location:   20:23027921-23028015question
Amplicon Length:   65
Splice Variants Targeted:   ENST00000377103

Gene Information

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease also known as inherited thrombophilia. [provided by RefSeq Jul 2008]

Gene Symbol:   THBD
Gene Name:   thrombomodulin
Aliases:   AHUS6, BDCA3, CD141, THRM, TM
RefSeq:   NC_000020.10 NG_012027.1 NT_011387.8
Ensembl:   ENSG00000178726
Entrez:   7056
Chromosome Mapping:   20p11.2

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