PrimePCR™ Probe Assay: S1PR5, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: S1PR5, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: S1PR5, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054689
Assay Design:   exonic
Chromosome Location:   19:10624159-10624279question
Amplicon Length:   91
Splice Variants Targeted:   ENST00000333430 ENST00000439028

Gene Information

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation apoptosis motility and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g. EDG1; MIM 601974) are S1P receptors; others (e.g. EDG2; MIM 602282) are LPA receptors.[supplied by OMIM Mar 2008]

Gene Symbol:   S1PR5
Gene Name:   sphingosine-1-phosphate receptor 5
Aliases:   EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
RefSeq:   NC_000019.9 NT_011295.11
Ensembl:   ENSG00000180739
Entrez:   53637
Chromosome Mapping:   19p13.2

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