PrimePCR™ Probe Assay: NOP10, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: NOP10, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: NOP10, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054770
Assay Design:   exonic
Chromosome Location:   15:34634150-34634251question
Amplicon Length:   72
Splice Variants Targeted:   ENST00000328848 ENST00000557912

Gene Information

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1 NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq Jul 2008]

Gene Symbol:   NOP10
Gene Name:   NOP10 ribonucleoprotein homolog (yeast)
Aliases:   MGC70651, NOLA3, NOP10P
RefSeq:   NC_000015.9 NG_007951.1 NG_011562.1 NT_010194.17
Ensembl:   ENSG00000182117
Entrez:   55505
Chromosome Mapping:   15q14-q15

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