PrimePCR™ Probe Assay: SPG7, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: SPG7, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SPG7, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055506
Assay Design:   exonic
Chromosome Location:   16:89575000-89579361question
Amplicon Length:   88
Splice Variants Targeted:   ENST00000566371 ENST00000268704 ENST00000341316 ENST00000568151

Gene Information

This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking intracellular motility organelle biogenesis protein folding and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq Jul 2008]

Gene Symbol:   SPG7
Gene Name:   spastic paraplegia 7 (pure and complicated autosomal recessive)
Aliases:   CAR, CMAR, FLJ37308, MGC126331, MGC126332, PGN, SPG5C
RefSeq:   NC_000016.9 NG_008082.1 NT_010542.15
Ensembl:   ENSG00000197912
Entrez:   6687
Chromosome Mapping:   16q24.3

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