PrimePCR™ Probe Assay: TUBA3C, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TUBA3C, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TUBA3C, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055524
Assay Design:   exonic
Chromosome Location:   13:19747912-19748013question
Amplicon Length:   72
Splice Variants Targeted:   ENST00000262510 ENST00000539144 ENST00000308149 ENST00000436936 ENST00000400113 ENST00000439976 ENST00000374338

Gene Information

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily which is composed of six distinct families. Genes from the alpha beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq Jul 2008]

Gene Symbol:   TUBA3C
Gene Name:   tubulin, alpha 3c
Aliases:   TUBA2, TUBA3D, bA408E5.3
RefSeq:   NC_000013.10 NT_024524.14
Ensembl:   ENSG00000198033
Entrez:   7278
Chromosome Mapping:   13q11

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