PrimePCR™ Probe Assay: CACNA1E, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CACNA1E, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CACNA1E, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055551
Assay Design:   exonic
Chromosome Location:   1:181453015-181479620question
Amplicon Length:   110
Splice Variants Targeted:   ENST00000524607 ENST00000367570 ENST00000526775 ENST00000360108 ENST00000367573 ENST00000357570 ENST00000358338 ENST00000367567

Gene Information

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1 alpha-2 beta and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes including muscle contraction hormone or neurotransmitter release gene expression cell motility cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Apr 2011]

Gene Symbol:   CACNA1E
Gene Name:   calcium channel, voltage-dependent, R type, alpha 1E subunit
Aliases:   BII, CACH6, CACNL1A6, Cav2.3
RefSeq:   NC_000001.10 NT_004487.19
Ensembl:   ENSG00000198216
Entrez:   777
Chromosome Mapping:   1q25-q31

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