PrimePCR™ Probe Assay: MTOR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: MTOR, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: MTOR, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055631
Assay Design:   exonic
Chromosome Location:   1:11174383-11174497question
Amplicon Length:   85
Splice Variants Targeted:   ENST00000376838 ENST00000361445 ENST00000455339

Gene Information

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq Sep 2008]

Gene Symbol:   MTOR
Gene Name:   mechanistic target of rapamycin (serine/threonine kinase)
Aliases:   FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
RefSeq:   NC_000001.10 NT_021937.19
Ensembl:   ENSG00000198793
Entrez:   2475
Chromosome Mapping:   1p36.2

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