PrimePCR™ Probe Assay: CD247, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055638
Assay Design:   exonic
Chromosome Location:   1:167400491-167400612question
Amplicon Length:   92
Splice Variants Targeted:   ENST00000362089 ENST00000392122

Gene Information

The protein encoded by this gene is T-cell receptor zeta which together with T-cell receptor alpha/beta and gamma/delta heterodimers and with CD3-gamma -delta and -epsilon forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CD247
Gene Name:   CD247 molecule
Aliases:   CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ
RefSeq:   NC_000001.10 NT_004487.19 NG_007384.1
Ensembl:   ENSG00000198821
Entrez:   919
Chromosome Mapping:   1q22-q23

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