PrimePCR™ Probe Assay: TRIM22, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0057571
Assay Design:   exonic
Chromosome Location:   11:5731116-5731234question
Amplicon Length:   89
Splice Variants Targeted:   ENST00000379965

Gene Information

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains a RING a B-box type 1 and a B-box type 2 and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq Dec 2010]

Gene Symbol:   TRIM22
Gene Name:   tripartite motif containing 22
Aliases:   GPSTAF50, RNF94, STAF50
RefSeq:   NC_000011.9 NT_009237.18
Ensembl:   ENSG00000132274
Entrez:   10346
Chromosome Mapping:   11p15

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