PrimePCR™ Probe Assay: KALRN, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: KALRN, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: KALRN, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0057943
Assay Design:   exonic
Chromosome Location:   3:123813633-123813740question
Amplicon Length:   78
Splice Variants Targeted:   ENST00000460856 ENST00000240874 ENST00000360013

Gene Information

Huntington's disease (HD) a neurodegenerative disorder characterized by loss of striatal neurons is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1 which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   KALRN
Gene Name:   kalirin, RhoGEF kinase
Aliases:   ARHGEF24, DUET, DUO, FLJ12332, FLJ16443, FLJ18196, FLJ18623, HAPIP, TRAD
RefSeq:   NC_000003.11 NG_012742.1 NT_005612.16
Ensembl:   ENSG00000160145
Entrez:   8997
Chromosome Mapping:   3q21.2

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