PrimePCR™ Probe Assay: DSC3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: DSC3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: DSC3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058086
Assay Design:   exonic
Chromosome Location:   18:28574183-28574319question
Amplicon Length:   107
Splice Variants Targeted:   ENST00000360428 ENST00000584980 ENST00000434452

Gene Information

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members along with the desmogleins are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18 occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   DSC3
Gene Name:   desmocollin 3
Aliases:   CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP
RefSeq:   NC_000018.9 NT_010966.14 NG_016782.1
Ensembl:   ENSG00000134762
Entrez:   1825
Chromosome Mapping:   18q12.1

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