PrimePCR™ Probe Assay: BAG2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058111
Assay Design:   exonic
Chromosome Location:   6:57048667-57048812question
Amplicon Length:   116
Splice Variants Targeted:   ENST00000545080 ENST00000438730 ENST00000370693

Gene Information

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1 BAG2 and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq Jul 2008]

Gene Symbol:   BAG2
Gene Name:   BCL2-associated athanogene 2
Aliases:   BAG-2, KIAA0576, MGC149462, dJ417I1.2
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000112208
Entrez:   9532
Chromosome Mapping:   6p12.1-p11.2

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