PrimePCR™ Probe Assay: CASQ2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CASQ2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CASQ2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058126
Assay Design:   exonic
Chromosome Location:   1:116243681-116243830question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000261448 ENST00000456138

Gene Information

The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2) a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq Jul 2008]

Gene Symbol:   CASQ2
Gene Name:   calsequestrin 2 (cardiac muscle)
Aliases:   FLJ26321, FLJ93514, PDIB2
RefSeq:   NC_000001.10 NG_008802.1 NG_016548.1 NT_032977.9
Ensembl:   ENSG00000118729
Entrez:   845
Chromosome Mapping:   1p13.3-p11

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