PrimePCR™ Probe Assay: SETD2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: SETD2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SETD2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058191
Assay Design:   exonic
Chromosome Location:   3:47164654-47164803question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000409792 ENST00000412450

Gene Information

Huntington's disease (HD) a neurodegenerative disorder characterized by loss of striatal neurons is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3 and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq Aug 2008]

Gene Symbol:   SETD2
Gene Name:   SET domain containing 2
Aliases:   FLJ16420, FLJ22472, FLJ23184, FLJ45883, FLJ46217, HBP231, HIF-1, HYPB, KIAA1732, KMT3A, SET2, p231HBP
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000181555
Entrez:   29072
Chromosome Mapping:   3p21.31

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