PrimePCR™ Probe Assay: TGFBI, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TGFBI, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TGFBI, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058394
Assay Design:   exonic
Chromosome Location:   5:135398918-135399016question
Amplicon Length:   69
Splice Variants Targeted:   ENST00000442011 ENST00000514554 ENST00000508076 ENST00000503087 ENST00000305126

Gene Information

This gene encodes an RGD-containing protein that binds to type I II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq Jul 2008]

Gene Symbol:   TGFBI
Gene Name:   transforming growth factor, beta-induced, 68kDa
Aliases:   BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, LCD1
RefSeq:   NC_000005.9 NG_012646.1 NT_034772.6
Ensembl:   ENSG00000120708
Entrez:   7045
Chromosome Mapping:   5q31

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