PrimePCR™ Probe Assay: PPARGC1B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PPARGC1B, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PPARGC1B, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026031
Assay Design:   Intron-spanning
Chromosome Location:   5:149219622-149221887question
Amplicon Length:   97
Splice Variants Targeted:   ENST00000360453 ENST00000394320 ENST00000309241 ENST00000403750 ENST00000434684

Gene Information

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors including estrogen receptor alpha nuclear respiratory factor 1 and glucocorticoid receptor. The encoded protein may be involved in fat oxidation non-oxidative glucose metabolism and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Mar 2010]

Gene Symbol:   PPARGC1B
Gene Name:   peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Aliases:   DKFZp686C1790, ERRL1, FLJ14284, PERC, PGC-1(beta), PGC1B
RefSeq:   NC_000005.9 NT_029289.11 NG_016747.1
Ensembl:   ENSG00000155846
Entrez:   133522
Chromosome Mapping:   5q32

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