PrimePCR™ Probe Assay: DMRT1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: DMRT1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: DMRT1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026083
Assay Design:   Intron-spanning
Chromosome Location:   9:847022-893941question
Amplicon Length:   122
Splice Variants Targeted:   ENST00000382276

Gene Information

This gene is found in a cluster with two other members of the gene family having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq Jul 2008]

Gene Symbol:   DMRT1
Gene Name:   doublesex and mab-3 related transcription factor 1
Aliases:   DMT1
RefSeq:   NC_000009.11 NG_009221.1 NT_008413.18
Ensembl:   ENSG00000137090
Entrez:   1761
Chromosome Mapping:   9p24.3

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