PrimePCR™ Probe Assay: PKD2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PKD2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PKD2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026127
Assay Design:   Intron-spanning
Chromosome Location:   4:88989125-88996050question
Amplicon Length:   146
Splice Variants Targeted:   ENST00000237596 ENST00000508588 ENST00000502363

Gene Information

This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1 and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq Mar 2011]

Gene Symbol:   PKD2
Gene Name:   polycystic kidney disease 2 (autosomal dominant)
Aliases:   APKD2, MGC138466, MGC138468, PC2, PKD4, Pc-2, TRPP2
RefSeq:   NC_000004.11 NG_008604.1 NT_016354.19
Ensembl:   ENSG00000118762
Entrez:   5311
Chromosome Mapping:   4q21-q23

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