PrimePCR™ Probe Assay: LRPPRC, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: LRPPRC, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: LRPPRC, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026417
Assay Design:   Intron-spanning
Chromosome Location:   2:44123791-44126419question
Amplicon Length:   89
Splice Variants Targeted:   ENST00000260665 ENST00000419884 ENST00000465633

Gene Information

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization vesicular transport or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq Mar 2012]

Gene Symbol:   LRPPRC
Gene Name:   leucine-rich PPR-motif containing
Aliases:   CLONE-23970, GP130, LRP130, LSFC
RefSeq:   NC_000002.11 NG_008247.1 NT_022184.15
Ensembl:   ENSG00000138095
Entrez:   10128
Chromosome Mapping:   2p21

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