PrimePCR™ Probe Assay: IL21, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026627
Assay Design:   Intron-spanning
Chromosome Location:   4:123536970-123542101question
Amplicon Length:   132
Splice Variants Targeted:   ENST00000264497

Gene Information

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation proliferation and activity of multiple target cells including macrophages natural killer cells B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Dec 2011]

Gene Symbol:   IL21
Gene Name:   interleukin 21
Aliases:   IL-21, Za11
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000138684
Entrez:   59067
Chromosome Mapping:   4q26-q27

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