PrimePCR™ Probe Assay: TNFAIP6, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: TNFAIP6, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TNFAIP6, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026740
Assay Design:   Intron-spanning
Chromosome Location:   2:152226669-152230095question
Amplicon Length:   97
Splice Variants Targeted:   ENST00000243347

Gene Information

The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I) and thus enhance the serine protease inhibitory activity of I alpha I which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq Dec 2010]

Gene Symbol:   TNFAIP6
Gene Name:   tumor necrosis factor, alpha-induced protein 6
Aliases:   TSG-6, TSG6
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000123610
Entrez:   7130
Chromosome Mapping:   2q23.3

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