PrimePCR™ Probe Assay: STK11, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: STK11, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: STK11, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026892
Assay Design:   Intron-spanning
Chromosome Location:   19:1207066-1218452question
Amplicon Length:   144
Splice Variants Targeted:   ENST00000326873 ENST00000405031

Gene Information

This gene which encodes a member of the serine/threonine kinase family regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract pigmented macules on the skin and mouth and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   STK11
Gene Name:   serine/threonine kinase 11
Aliases:   LKB1, PJS
RefSeq:   NC_000019.9 NG_007460.1 NT_011255.14
Ensembl:   ENSG00000118046
Entrez:   6794
Chromosome Mapping:   19p13.3

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