PrimePCR™ Probe Assay: CYSLTR1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CYSLTR1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CYSLTR1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026964
Assay Design:   Intron-spanning
Chromosome Location:   X:77529184-77539015question
Amplicon Length:   122
Splice Variants Targeted:   ENST00000373304

Gene Information

The cysteinyl leukotrienes LTC4 LTD4 and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle oedema eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq Jul 2008]

Gene Symbol:   CYSLTR1
Gene Name:   cysteinyl leukotriene receptor 1
Aliases:   CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139
RefSeq:   NC_000023.10 NG_012809.1 NT_011651.17
Ensembl:   ENSG00000173198
Entrez:   10800
Chromosome Mapping:   Xq13.2-q21.1

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